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Protein tyrosine kinase 2: a novel therapeutic target to overcome acquired EGFR-TKI resistance in non-small cell lung cancer

BACKGROUND: Protein tyrosine kinase 2 (PTK2) expression has been reported in various types of human epithelial cancers including lung cancer; however, the role of PTK2 in epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer (NSCLC) has not been elucidated. We previously reported...

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Detalles Bibliográficos
Autores principales: Tong, Xuexia, Tanino, Ryosuke, Sun, Rong, Tsubata, Yukari, Okimoto, Tamio, Takechi, Mayumi, Isobe, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889213/
https://www.ncbi.nlm.nih.gov/pubmed/31791326
http://dx.doi.org/10.1186/s12931-019-1244-2