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Genome-Wide Profiling of Acquired Uniparental Disomy Reveals Prognostic Factors in Head and Neck Squamous Cell Carcinoma

Acquired uniparental disomy (aUPD) leads to homozygosity facilitating identification of monoallelically expressed genes. We analyzed single-nucleotide polymorphism array-based genotyping data of 448 head and neck squamous cell carcinoma (HNSCC) samples from The Cancer Genome Atlas to determine the f...

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Detalles Bibliográficos
Autores principales: Tuna, Musaffe, Liu, Wenbin, Amos, Christopher I., Mills, Gordon B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889229/
https://www.ncbi.nlm.nih.gov/pubmed/31734631
http://dx.doi.org/10.1016/j.neo.2019.08.008