Therapeutic resistance and susceptibility is shaped by cooperative multi-compartment tumor adaptation

Emerging research suggests that multiple tumor compartments can influence treatment responsiveness and relapse, yet the search for therapeutic resistance mechanisms remains largely focused on acquired genomic alterations in cancer cells. Here we show how treatment-induced changes occur in multiple t...

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Detalles Bibliográficos
Autores principales: Long, Jason E., Wongchenko, Matthew J., Nickles, Dorothee, Chung, Wei-Jen, Wang, Bu-er, Riegler, Johannes, Li, Ji, Li, Qingling, Sandoval, Wendy, Eastham-Anderson, Jeff, Modrusan, Zora, Junttila, Teemu, Carano, Richard A. D., Foreman, Oded, Yan, Yibing, Junttila, Melissa R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889278/
https://www.ncbi.nlm.nih.gov/pubmed/30824837
http://dx.doi.org/10.1038/s41418-019-0310-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889278/
https://www.ncbi.nlm.nih.gov/pubmed/30824837
http://dx.doi.org/10.1038/s41418-019-0310-0

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