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LRIG1 is a pleiotropic androgen receptor-regulated feedback tumor suppressor in prostate cancer

LRIG1 has been reported to be a tumor suppressor in gastrointestinal tract and epidermis. However, little is known about the expression, regulation and biological functions of LRIG1 in prostate cancer (PCa). We find that LRIG1 is overexpressed in PCa, but its expression correlates with better patien...

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Detalles Bibliográficos
Autores principales: Li, Qiuhui, Liu, Bigang, Chao, Hsueh-Ping, Ji, Yibing, Lu, Yue, Mehmood, Rashid, Jeter, Collene, Chen, Taiping, Moore, John R., Li, Wenqian, Liu, Can, Rycaj, Kiera, Tracz, Amanda, Kirk, Jason, Calhoun-Davis, Tammy, Xiong, Jie, Deng, Qu, Huang, Jiaoti, Foster, Barbara A., Gokhale, Abhiram, Chen, Xin, Tang, Dean G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889295/
https://www.ncbi.nlm.nih.gov/pubmed/31792211
http://dx.doi.org/10.1038/s41467-019-13532-4