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Peripheral blood mononuclear cell transcriptomes reveal an over-representation of down-regulated genes associated with immunity in HIV-exposed uninfected infants

HIV-exposed uninfected (HEU) infants are disproportionately at a higher risk of morbidity and mortality, as compared to HIV-unexposed uninfected (HUU) infants. Here, we used transcriptional profiling of peripheral blood mononuclear cells to determine immunological signatures of in utero HIV exposure...

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Detalles Bibliográficos
Autores principales: Musimbi, Zaneta D., Rono, Martin K., Otieno, James R., Kibinge, Nelson, Ochola-Oyier, Lynette Isabella, de Villiers, Etienne Pierre, Nduati, Eunice W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889308/
https://www.ncbi.nlm.nih.gov/pubmed/31792230
http://dx.doi.org/10.1038/s41598-019-54083-4