Cellular hypoxia promotes osteogenic differentiation of mesenchymal stem cells and bone defect healing via STAT3 signaling

BACKGROUND: Hypoxia in the vicinity of bone defects triggers the osteogenic differentiation of precursor cells and promotes healing. The activation of STAT3 signaling in mesenchymal stem cells (MSCs) has similarly been reported to mediate bone regeneration. However, the interaction between hypoxia a...

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Detalles Bibliográficos
Autores principales: Yu, Xin, Wan, Qilong, Ye, Xiaoling, Cheng, Yuet, Pathak, Janak L., Li, Zubing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889321/
https://www.ncbi.nlm.nih.gov/pubmed/31827540
http://dx.doi.org/10.1186/s11658-019-0191-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889321/
https://www.ncbi.nlm.nih.gov/pubmed/31827540
http://dx.doi.org/10.1186/s11658-019-0191-8

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