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Thawed Mesenchymal Stem Cell Product Shows Comparable Immunomodulatory Potency to Cultured Cells In Vitro and in Polymicrobial Septic Animals

Mesenchymal stem cells (MSCs) have been shown to exert immunomodulatory effects in both acute and chronic diseases. In acute inflammatory conditions like sepsis, cell therapy must be administered within hours of diagnosis, requiring “off-the-shelf” cryopreserved allogeneic cell products. However, th...

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Detalles Bibliográficos
Autores principales: Tan, Yuan, Salkhordeh, Mahmoud, Wang, Jia-Pey, McRae, Andrea, Souza-Moreira, Luciana, McIntyre, Lauralyn, Stewart, Duncan J., Mei, Shirley H. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889371/
https://www.ncbi.nlm.nih.gov/pubmed/31792313
http://dx.doi.org/10.1038/s41598-019-54462-x