LIN28B affects gene expression at the hypothalamic-pituitary axis and serum testosterone levels

Genome-wide association studies (GWAS) have recurrently associated sequence variation nearby LIN28B with pubertal timing, growth and disease. However, the biology linking LIN28B with these traits is still poorly understood. With our study, we sought to elucidate the mechanisms behind the LIN28B asso...

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Detalles Bibliográficos
Autores principales: Leinonen, Jaakko T., Chen, Yu-Chia, Pennonen, Jana, Lehtonen, Leevi, Junna, Nella, Tukiainen, Taru, Panula, Pertti, Widén, Elisabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889388/
https://www.ncbi.nlm.nih.gov/pubmed/31792362
http://dx.doi.org/10.1038/s41598-019-54475-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889388/
https://www.ncbi.nlm.nih.gov/pubmed/31792362
http://dx.doi.org/10.1038/s41598-019-54475-6

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