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Prediction of leukocyte counts during paediatric acute lymphoblastic leukaemia maintenance therapy
Maintenance chemotherapy with oral 6-mercaptopurine and methotrexate remains a cornerstone of modern therapy for acute lymphoblastic leukaemia. The dosage and intensity of therapy are based on surrogate markers such as peripheral blood leukocyte and neutrophil counts. Dosage based leukocyte count pr...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889389/ https://www.ncbi.nlm.nih.gov/pubmed/31792398 http://dx.doi.org/10.1038/s41598-019-54492-5 |