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Prediction of leukocyte counts during paediatric acute lymphoblastic leukaemia maintenance therapy

Maintenance chemotherapy with oral 6-mercaptopurine and methotrexate remains a cornerstone of modern therapy for acute lymphoblastic leukaemia. The dosage and intensity of therapy are based on surrogate markers such as peripheral blood leukocyte and neutrophil counts. Dosage based leukocyte count pr...

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Detalles Bibliográficos
Autores principales:	Karppinen, Santeri, Lohi, Olli, Vihola, Matti
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889389/ https://www.ncbi.nlm.nih.gov/pubmed/31792398 http://dx.doi.org/10.1038/s41598-019-54492-5

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