6-Bromoindirubin-3′-oxime intercepts GSK3 signaling to promote and enhance skeletal muscle differentiation affecting miR-206 expression in mice

Dystrophies are characterized by progressive skeletal muscle degeneration and weakness as consequence of their molecular abnormalities. Thus, new drugs for restoring skeletal muscle deterioration are critically needed. To identify new and alternative compounds with a functional role in skeletal musc...

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Detalles Bibliográficos
Autores principales: Ragozzino, Elvira, Brancaccio, Mariarita, Di Costanzo, Antonella, Scalabrì, Francesco, Andolfi, Gennaro, Wanderlingh, Luca G., Patriarca, Eduardo J., Minchiotti, Gabriella, Altamura, Sergio, Varrone, Francesca, Summa, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889408/
https://www.ncbi.nlm.nih.gov/pubmed/31792344
http://dx.doi.org/10.1038/s41598-019-54574-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889408/
https://www.ncbi.nlm.nih.gov/pubmed/31792344
http://dx.doi.org/10.1038/s41598-019-54574-4

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