Derepression of LOXL4 inhibits liver cancer growth by reactivating compromised p53

TP53 is the most frequently mutated gene in human cancer, whereas tumors with wild-type TP53 develop alternative strategies to survive. Identifying new regulators of p53 reactivation would greatly contribute to the development of cancer therapies. After screening the entire genome in liver cancer ce...

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Detalles Bibliográficos
Autores principales: Shao, Jialiang, Lu, Jiongjiong, Zhu, Wencheng, Yu, Hua, Jing, Xiaoqian, Wang, Yi-Lin, Wang, Xiang, Wang, Xiong-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889417/
https://www.ncbi.nlm.nih.gov/pubmed/30728460
http://dx.doi.org/10.1038/s41418-019-0293-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889417/
https://www.ncbi.nlm.nih.gov/pubmed/30728460
http://dx.doi.org/10.1038/s41418-019-0293-x

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