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Derepression of LOXL4 inhibits liver cancer growth by reactivating compromised p53
TP53 is the most frequently mutated gene in human cancer, whereas tumors with wild-type TP53 develop alternative strategies to survive. Identifying new regulators of p53 reactivation would greatly contribute to the development of cancer therapies. After screening the entire genome in liver cancer ce...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889417/ https://www.ncbi.nlm.nih.gov/pubmed/30728460 http://dx.doi.org/10.1038/s41418-019-0293-x |