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A panel of DNA methylated markers predicts metastasis of pN(0)M(0) gastric carcinoma: a prospective cohort study

BACKGROUND: The aim of this prospective study was to evaluate the feasibility of predicting GC metastasis using CDH1, GFRA1, P16 and ZNF382 DNA methylation as biomarkers. METHODS: 198 GC patients without metastasis at the time of surgery resection were recruited into the double-blind cohort (NCT0215...

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Detalles Bibliográficos
Autores principales: Liu, Zhaojun, Cheng, Xiaojing, Zhang, Lianhai, Zhou, Jing, Deng, Dajun, Ji, Jiafu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889426/
https://www.ncbi.nlm.nih.gov/pubmed/31431673
http://dx.doi.org/10.1038/s41416-019-0552-0