Imaging of intermittent lipid-receptor interactions reflects changes in live cell membranes upon agonist-receptor binding

Protein-lipid interactions in cellular membranes modulate central cellular functions, are often transient in character, but occur too intermittently to be readily observable. We introduce transient state imaging (TRAST), combining sensitive fluorescence detection of fluorophore markers with monitori...

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Detalles Bibliográficos
Autores principales: Tornmalm, Johan, Piguet, Joachim, Chmyrov, Volodymyr, Widengren, Jerker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889430/
https://www.ncbi.nlm.nih.gov/pubmed/31792325
http://dx.doi.org/10.1038/s41598-019-54625-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889430/
https://www.ncbi.nlm.nih.gov/pubmed/31792325
http://dx.doi.org/10.1038/s41598-019-54625-w

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