PYK2 Is Involved in Premalignant Acinar Cell Reprogramming and Pancreatic Ductal Adenocarcinoma Maintenance by Phosphorylating β-Catenin(Y654)

BACKGROUND & AIMS: Identification and validation of new functionally relevant and pharmacologically actionable targets for pancreatic ductal adenocarcinoma (PDAC) remains a great challenge. Premalignant acinar cell reprogramming (acinar-to-ductal metaplasia [ADM]) is a precursor of pancreatic in...

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Detalles Bibliográficos
Autores principales: Gao, Chenxi, Chen, Guangming, Zhang, Dennis Han, Zhang, Judy, Kuan, Shih-Fan, Hu, Wenhuo, Esni, Farzad, Gao, Xuan, Guan, Jun-Lin, Chu, Edward, Hu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889497/
https://www.ncbi.nlm.nih.gov/pubmed/31330317
http://dx.doi.org/10.1016/j.jcmgh.2019.07.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889497/
https://www.ncbi.nlm.nih.gov/pubmed/31330317
http://dx.doi.org/10.1016/j.jcmgh.2019.07.004

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