EWS-FLI1-mediated tenascin-C expression promotes tumour progression by targeting MALAT1 through integrin α5β1-mediated YAP activation in Ewing sarcoma

BACKGROUND: The extracellular matrix has been critically associated with the tumorigenesis and progression of Ewing sarcoma (ES). However, the regulatory and prognostic roles of tenascin-C (TNC) in ES remain unclear. METHODS: TNC expression was examined in specimens by immunohistochemistry, and the...

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Detalles Bibliográficos
Autores principales: He, Shaohui, Huang, Quan, Hu, Jinbo, Li, Lei, Xiao, Yanbin, Yu, Hongyu, Han, Zhitao, Wang, Ting, Zhou, Wang, Wei, Haifeng, Xiao, Jianru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889507/
https://www.ncbi.nlm.nih.gov/pubmed/31649319
http://dx.doi.org/10.1038/s41416-019-0608-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889507/
https://www.ncbi.nlm.nih.gov/pubmed/31649319
http://dx.doi.org/10.1038/s41416-019-0608-1

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