Key role of UBQLN2 in pathogenesis of amyotrophic lateral sclerosis and frontotemporal dementia

Ubiquilin-2 (UBQLN2) is a member of the ubiquilin family, actively implicated in the degradation of misfolded and redundant proteins through the ubiquitin-proteasome system and macroautophagy. UBQLN2 received much attention after the discovery of gene mutations in amyotrophic lateral sclerosis and f...

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Detalles Bibliográficos
Autores principales: Renaud, Laurence, Picher-Martel, Vincent, Codron, Philippe, Julien, Jean-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889556/
https://www.ncbi.nlm.nih.gov/pubmed/31319884
http://dx.doi.org/10.1186/s40478-019-0758-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889556/
https://www.ncbi.nlm.nih.gov/pubmed/31319884
http://dx.doi.org/10.1186/s40478-019-0758-7

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