Plasmodium Secretion Induces Hepatocyte Lysosome Exocytosis and Promotes Parasite Entry

The invasion of a suitable host hepatocyte by Plasmodium sporozoites is an essential step in malaria infection. We demonstrate that in infected hepatocytes, lysosomes are redistributed away from the nucleus, and surface exposure of lysosome-associated membrane protein 1 (LAMP1) is increased. Lysosom...

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Detalles Bibliográficos
Autores principales: Vijayan, Kamalakannan, Cestari, Igor, Mast, Fred D., Glennon, Elizabeth K.K., McDermott, Suzanne M., Kain, Heather S., Brokaw, Alyssa M., Aitchison, John D., Stuart, Kenneth, Kaushansky, Alexis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889558/
https://www.ncbi.nlm.nih.gov/pubmed/31731198
http://dx.doi.org/10.1016/j.isci.2019.10.054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889558/
https://www.ncbi.nlm.nih.gov/pubmed/31731198
http://dx.doi.org/10.1016/j.isci.2019.10.054

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