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Multiple selective sweeps of ancient polymorphisms in and around LTα located in the MHC class III region on chromosome 6
BACKGROUND: Lymphotoxin-α (LTα), located in the Major Histocompatibility Complex (MHC) class III region on chromosome 6, encodes a cytotoxic protein that mediates a variety of antiviral responses among other biological functions. Furthermore, several genotypes at this gene have been implicated in th...
Autores principales: | Campbell, Michael C., Ashong, Bryan, Teng, Shaolei, Harvey, Jayla, Cross, Christopher N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889576/ https://www.ncbi.nlm.nih.gov/pubmed/31791241 http://dx.doi.org/10.1186/s12862-019-1516-y |
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