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Relationship between the effects of food on the pharmacokinetics of oral antineoplastic drugs and their physicochemical properties

BACKGROUND: Food is known to affect drug absorption by delaying gastric emptying time, altering gastrointestinal pH, stimulating bile flow, increasing splanchnic blood flow, or physically interacting with drugs. Although food is known to affect the pharmacokinetics of oral antineoplastic drugs, the...

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Detalles Bibliográficos
Autores principales: Omachi, Fukiko, Kaneko, Masaki, Iijima, Ryosuke, Watanabe, Machiko, Itagaki, Fumio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889584/
https://www.ncbi.nlm.nih.gov/pubmed/31827876
http://dx.doi.org/10.1186/s40780-019-0155-1