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Deciphering the Gene Regulatory Landscape Encoded in DNA Biophysical Features
Gene regulation in higher organisms involves a sophisticated interplay between genetic and epigenetic mechanisms. Despite advances, the logic in selective usage of certain genomic regions as regulatory elements remains unclear. Here we show that the inherent biophysical properties of the DNA encode...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889597/ https://www.ncbi.nlm.nih.gov/pubmed/31731201 http://dx.doi.org/10.1016/j.isci.2019.10.055 |