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Circadian sleep/wake-associated cells show dipeptide repeat protein aggregates in C9orf72-related ALS and FTLD cases

Motor-, behavior- and/or cognition-related symptoms are key hallmarks in patients with amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) with TDP-43 pathology (FTLD-TDP), respectively. It has been reported that these patients also experience sleep disturbances, which m...

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Detalles Bibliográficos
Autores principales: Dedeene, Lieselot, Van Schoor, Evelien, Vandenberghe, Rik, Van Damme, Philip, Poesen, Koen, Thal, Dietmar Rudolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889626/
https://www.ncbi.nlm.nih.gov/pubmed/31791419
http://dx.doi.org/10.1186/s40478-019-0845-9