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An improved random forest-based computational model for predicting novel miRNA-disease associations

BACKGROUND: A large body of evidence shows that miRNA regulates the expression of its target genes at post-transcriptional level and the dysregulation of miRNA is related to many complex human diseases. Accurately discovering disease-related miRNAs is conductive to the exploring of the pathogenesis...

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Detalles Bibliográficos
Autores principales: Yao, Dengju, Zhan, Xiaojuan, Kwoh, Chee-Keong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889672/
https://www.ncbi.nlm.nih.gov/pubmed/31795954
http://dx.doi.org/10.1186/s12859-019-3290-7