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Age-related transcriptome changes in Sox2+ supporting cells in the mouse cochlea

BACKGROUND: Inner ear supporting cells (SCs) in the neonatal mouse cochlea are a potential source for hair cell (HC) regeneration, but several studies have shown that the regeneration ability of SCs decreases dramatically as mice age and that lost HCs cannot be regenerated in adult mice. To better u...

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Detalles Bibliográficos
Autores principales: Cheng, Cheng, Wang, Yunfeng, Guo, Luo, Lu, Xiaoling, Zhu, Weijie, Muhammad, Waqas, Zhang, Liyan, Lu, Ling, Gao, Junyan, Tang, Mingliang, Chen, Fangyi, Gao, Xia, Li, Huawei, Chai, Renjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889721/
https://www.ncbi.nlm.nih.gov/pubmed/31791390
http://dx.doi.org/10.1186/s13287-019-1437-0