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Relationship between diffusion capacity and small airway abnormality in COPDGene

ABSTRACT: Impaired single breath carbon monoxide diffusing capacity (DLCO) is associated with emphysema. Small airways disease (SAD) may be a precursor lesion to emphysema, but the relationship between SAD and DLCO is undescribed. We hypothesized that in mild COPD, functional SAD (fSAD) defined by c...

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Detalles Bibliográficos
Autores principales: Criner, Rachel N., Hatt, Charles R., Galbán, Craig J., Kazerooni, Ella A., Lynch, David A., McCormack, Meredith C., Casaburi, Richard, MacIntyre, Neil R., Make, Barry J., Martinez, Fernando J., Labaki, Wassim W., Curtis, Jeffrey L., Han, Mei Lan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889734/
https://www.ncbi.nlm.nih.gov/pubmed/31791337
http://dx.doi.org/10.1186/s12931-019-1237-1