A screening-based approach identifies cell cycle regulators AURKA, CHK1 and PLK1 as targetable regulators of chondrosarcoma cell survival

Chondrosarcomas are malignant cartilage tumors that are relatively resistant towards conventional therapeutic approaches. Kinase inhibitors have been investigated and shown successful for several different cancer types. In this study we aimed at identifying kinase inhibitors that inhibit the surviva...

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Detalles Bibliográficos
Autores principales: de Jong, Yvonne, Bennani, Fairuz, van Oosterwijk, Jolieke G., Alberti, Gaia, Baranski, Zuzanna, Wijers-Koster, Pauline, Venneker, Sanne, Briaire-de Bruijn, Inge H., van de Akker, Brendy E., Baelde, Hans, Cleton-Jansen, Anne-Marie, van de Water, Bob, Danen, Erik H.J., Bovée, Judith V.M.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889735/
https://www.ncbi.nlm.nih.gov/pubmed/31832331
http://dx.doi.org/10.1016/j.jbo.2019.100268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889735/
https://www.ncbi.nlm.nih.gov/pubmed/31832331
http://dx.doi.org/10.1016/j.jbo.2019.100268

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