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PPARα ligand, AVE8134, and cyclooxygenase inhibitor therapy synergistically suppress lung cancer growth and metastasis

BACKGROUND: Lung cancer (LC) is one of the leading causes of death worldwide, which highlights the urgent need for better therapies. Peroxisome proliferator-activated nuclear receptor alpha (PPARα), known as a key nuclear transcription factor involved in glucose and lipid metabolism, has been also i...

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Detalles Bibliográficos
Autores principales: Wu, Lujin, Wang, Wei, Dai, Meiyan, Li, Huihui, Chen, Chen, Wang, Daowen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889744/
https://www.ncbi.nlm.nih.gov/pubmed/31791289
http://dx.doi.org/10.1186/s12885-019-6379-5