Genomic Profiling of Biliary Tract Cancer Cell Lines Reveals Molecular Subtypes and Actionable Drug Targets

Biliary tract cancers (BTCs) currently have no approved targeted therapies. Although genomic profiling of primary BTCs has identified multiple potential drug targets, accurate models are needed for their evaluation. Genomic profiling of 22 BTC cell lines revealed they harbor similar mutational signa...

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Detalles Bibliográficos
Autores principales: Lau, David K., Mouradov, Dmitri, Wasenang, Wiphawan, Luk, Ian Y., Scott, Cameron M., Williams, David S., Yeung, Yvonne H., Limpaiboon, Temduang, Iatropoulos, George F., Jenkins, Laura J., Reehorst, Camilla M., Chionh, Fiona, Nikfarjam, Mehrdad, Croagh, Daniel, Dhillon, Amardeep S., Weickhardt, Andrew J., Muramatsu, Toshihide, Saito, Yoshimasa, Tebbutt, Niall C., Sieber, Oliver M., Mariadason, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889747/
https://www.ncbi.nlm.nih.gov/pubmed/31731200
http://dx.doi.org/10.1016/j.isci.2019.10.044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889747/
https://www.ncbi.nlm.nih.gov/pubmed/31731200
http://dx.doi.org/10.1016/j.isci.2019.10.044

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