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Role of KCNQ potassium channels in stress-induced deficit of working memory

The prefrontal cortex (PFC) mediates higher cognition but is impaired by stress exposure when high levels of catecholamines activate calcium-cAMP-protein kinase A (PKA) signaling. The current study examined whether stress and increased cAMP-PKA signaling in rat medial PFC (mPFC) reduce pyramidal cel...

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Detalles Bibliográficos
Autores principales: Arnsten, Amy F.T., Jin, Lu E., Gamo, Nao J., Ramos, Brian, Paspalas, Constantinos D., Morozov, Yury M., Kata, Anna, Bamford, Nigel S., Yeckel, Mark F., Kaczmarek, Leonard K., El-Hassar, Lynda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889760/
https://www.ncbi.nlm.nih.gov/pubmed/31832507
http://dx.doi.org/10.1016/j.ynstr.2019.100187