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Rasagiline, a monoamine oxidase B inhibitor, reduces in vivo [(18)F]THK5351 uptake in progressive supranuclear palsy

BACKGROUND: [(18)F]THK5351 is a tau positron emission tomography tracer that has shown promise in quantifying tau distribution in tauopathies such as Alzheimer's disease (AD) and progressive supranuclear palsy (PSP). However, the interpretation of [(18)F]THK5351 uptake has been shown to be conf...

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Detalles Bibliográficos
Autores principales: Ng, Kok Pin, Therriault, Joseph, Kang, Min Su, Struyfs, Hanne, Pascoal, Tharick A, Mathotaarachchi, Sulantha, Shin, Monica, Benedet, Andrea L, Massarweh, Gassan, Soucy, Jean-Paul, Neto, Pedro Rosa, Gauthier, Serge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889764/
https://www.ncbi.nlm.nih.gov/pubmed/31795034
http://dx.doi.org/10.1016/j.nicl.2019.102091