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Molecular replacement using structure predictions from databases

Molecular replacement (MR) is the predominant route to solution of the phase problem in macromolecular crystallography. Where the lack of a suitable homologue precludes conventional MR, one option is to predict the target structure using bioinformatics. Such modelling, in the absence of homologous t...

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Detalles Bibliográficos
Autores principales: Simpkin, Adam J., Thomas, Jens M. H., Simkovic, Felix, Keegan, Ronan M., Rigden, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889911/
https://www.ncbi.nlm.nih.gov/pubmed/31793899
http://dx.doi.org/10.1107/S2059798319013962