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Loss of LAMTOR1 in pancreatic β-cells increases glucose-stimulated insulin secretion in mice

Insulin secretion from pancreatic β-cells regulates glucose metabolism and is related to various diseases including diabetes. The late endosomal/lysosomal adaptor MAPK and mTOR activator 1 (LAMTOR1) is one of the subunits of the 'Ragulator' complex and plays an important role in energy met...

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Detalles Bibliográficos
Autores principales: Huang, Qiong, Gong, Qi, Wen, Ting, Feng, Shanshan, Xu, Jixiong, Liu, Jianying, Han, Xiudan, Liu, Qun, Hu, Juan, Zhu, Lingyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889919/
https://www.ncbi.nlm.nih.gov/pubmed/31939616
http://dx.doi.org/10.3892/ijmm.2019.4409