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Loss of LAMTOR1 in pancreatic β-cells increases glucose-stimulated insulin secretion in mice
Insulin secretion from pancreatic β-cells regulates glucose metabolism and is related to various diseases including diabetes. The late endosomal/lysosomal adaptor MAPK and mTOR activator 1 (LAMTOR1) is one of the subunits of the 'Ragulator' complex and plays an important role in energy met...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889919/ https://www.ncbi.nlm.nih.gov/pubmed/31939616 http://dx.doi.org/10.3892/ijmm.2019.4409 |