Rapamycin regulates the balance between cardiomyocyte apoptosis and autophagy in chronic heart failure by inhibiting mTOR signaling

The progressive loss of cardiomyocytes caused by cell death leads to cardiac dysfunction and heart failure (HF). Rapamycin has been shown to be cardioprotective in pressure-overloaded and ischemic heart diseases by regulating the mechanistic target of rapamycin (mTOR) signaling network. However, the...

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Detalles Bibliográficos
Autores principales: Gao, Guangyuan, Chen, Weiwei, Yan, Mengjie, Liu, Jinsha, Luo, Huiling, Wang, Chang, Yang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889932/
https://www.ncbi.nlm.nih.gov/pubmed/31746373
http://dx.doi.org/10.3892/ijmm.2019.4407

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889932/
https://www.ncbi.nlm.nih.gov/pubmed/31746373
http://dx.doi.org/10.3892/ijmm.2019.4407

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