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Hypoxic mast cells accelerate the proliferation, collagen accumulation and phenotypic alteration of human lung fibroblasts

Pulmonary vascular remodeling and fibrosis are the critical pathological characteristics of hypoxic pulmonary hypertension. Our previous study demonstrated that hypoxia is involved in the functional alteration of lung fibroblasts, but the underlying mechanism has yet to be fully elucidated. The aim...

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Detalles Bibliográficos
Autores principales: Wang, Xiang, Lin, Lianjun, Chai, Xiaoyu, Wu, Yanping, Li, Yong, Liu, Xinmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889934/
https://www.ncbi.nlm.nih.gov/pubmed/31746371
http://dx.doi.org/10.3892/ijmm.2019.4400