Honokiol antagonizes doxorubicin-induced cardiomyocyte senescence by inhibiting TXNIP-mediated NLRP3 inflammasome activation

Senescence of cardiomyocytes is considered a key factor for the occurrence of doxorubicin (Dox)-associated cardiomyopathy. The NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome is reported to be involved in the process of cellular senescence. Furthermore, thioredoxin-interactiv...

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Detalles Bibliográficos
Autores principales: Huang, Pian-Pian, Fu, Jun, Liu, Li-Hua, Wu, Ke-Fei, Liu, Hong-Xia, Qi, Ben-Ming, Liu, Yun, Qi, Ben-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889937/
https://www.ncbi.nlm.nih.gov/pubmed/31746354
http://dx.doi.org/10.3892/ijmm.2019.4393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889937/
https://www.ncbi.nlm.nih.gov/pubmed/31746354
http://dx.doi.org/10.3892/ijmm.2019.4393

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