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Paradoxical Changes Underscore Epigenetic Reprogramming During Adult Zebrafish Extraocular Muscle Regeneration

PURPOSE: Genomic reprogramming and cellular dedifferentiation are critical to the success of de novo tissue regeneration in lower vertebrates such as zebrafish and axolotl. In tissue regeneration following injury or disease, differentiated cells must retain lineage while assuming a progenitor-like i...

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Detalles Bibliográficos
Autores principales: Tingle, Christina F., Magnuson, Brian, Zhao, Yi, Heisel, Curtis J., Kish, Phillip E., Kahana, Alon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890397/
https://www.ncbi.nlm.nih.gov/pubmed/31794598
http://dx.doi.org/10.1167/iovs.19-27556