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Cerebellar nuclei excitatory neurons regulate developmental scaling of presynaptic Purkinje cell number and organ growth

For neural systems to function effectively, the numbers of each cell type must be proportioned properly during development. We found that conditional knockout of the mouse homeobox genes En1 and En2 in the excitatory cerebellar nuclei neurons (eCN) leads to reduced postnatal growth of the cerebellar...

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Detalles Bibliográficos
Autores principales: Willett, Ryan T, Bayin, N Sumru, Lee, Andrew S, Krishnamurthy, Anjana, Wojcinski, Alexandre, Lao, Zhimin, Stephen, Daniel, Rosello-Diez, Alberto, Dauber-Decker, Katherine L, Orvis, Grant D, Wu, Zhuhao, Tessier-Lavigne, Marc, Joyner, Alexandra L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890462/
https://www.ncbi.nlm.nih.gov/pubmed/31742552
http://dx.doi.org/10.7554/eLife.50617