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Long Non-Coding RNA NEAT1 Promoted Hepatocellular Carcinoma Cell Proliferation and Reduced Apoptosis Through the Regulation of Let-7b-IGF-1R Axis

BACKGROUND AND AIM: Long non-coding RNA nuclear-enriched abundant transcript 1 (NEAT1) is abnormally expressed in various human malignancies, including hepatocellular carcinoma (HCC). Let-7b is a miRNA with the effect of a tumor suppressor gene, and its expression level in various tumor tissues is l...

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Detalles Bibliográficos
Autores principales: Liu, Qin, Shi, Hexian, Yang, Jianbo, Jiang, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890520/
https://www.ncbi.nlm.nih.gov/pubmed/31819522
http://dx.doi.org/10.2147/OTT.S217763