Cargando…

Orthogonal regulation of DNA nanostructure self-assembly and disassembly using antibodies

Here we report a rational strategy to orthogonally control assembly and disassembly of DNA-based nanostructures using specific IgG antibodies as molecular inputs. We first demonstrate that the binding of a specific antibody to a pair of antigen-conjugated split DNA input-strands induces their co-loc...

Descripción completa

Detalles Bibliográficos
Autores principales: Ranallo, Simona, Sorrentino, Daniela, Ricci, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890650/
https://www.ncbi.nlm.nih.gov/pubmed/31796740
http://dx.doi.org/10.1038/s41467-019-13104-6