Computational STAT3 activity inference reveals its roles in the pancreatic tumor microenvironment

Transcription factor (TF) STAT3 contributes to pancreatic cancer progression through its regulatory roles in both tumor cells and the tumor microenvironment (TME). In this study, we performed a systematic analysis of all TFs in patient-derived gene expression datasets and confirmed STAT3 as a critic...

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Detalles Bibliográficos
Autores principales: Schaafsma, Evelien, Yuan, Yiwei, Zhao, Yanding, Cheng, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890662/
https://www.ncbi.nlm.nih.gov/pubmed/31796877
http://dx.doi.org/10.1038/s41598-019-54791-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890662/
https://www.ncbi.nlm.nih.gov/pubmed/31796877
http://dx.doi.org/10.1038/s41598-019-54791-x

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