Cargando…
Computational STAT3 activity inference reveals its roles in the pancreatic tumor microenvironment
Transcription factor (TF) STAT3 contributes to pancreatic cancer progression through its regulatory roles in both tumor cells and the tumor microenvironment (TME). In this study, we performed a systematic analysis of all TFs in patient-derived gene expression datasets and confirmed STAT3 as a critic...
Autores principales: | Schaafsma, Evelien, Yuan, Yiwei, Zhao, Yanding, Cheng, Chao |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890662/ https://www.ncbi.nlm.nih.gov/pubmed/31796877 http://dx.doi.org/10.1038/s41598-019-54791-x |
Ejemplares similares
-
Gene signature‐based prediction of triple‐negative breast cancer patient response to Neoadjuvant chemotherapy
por: Zhao, Yanding, et al.
Publicado: (2020) -
TimiGP: Inferring cell-cell interactions and prognostic associations in the tumor immune microenvironment through gene pairs
por: Li, Chenyang, et al.
Publicado: (2023) -
B cell infiltration is highly associated with prognosis and an immune-infiltrated tumor microenvironment in neuroblastoma
por: Schaafsma, Evelien, et al.
Publicado: (2021) -
AutoEncoder-Based Computational Framework for Tumor Microenvironment Decomposition and Biomarker Identification in Metastatic Melanoma
por: Zhao, Yanding, et al.
Publicado: (2021) -
Influence of T Cell-Mediated Immune Surveillance on Somatic Mutation Occurrences in Melanoma
por: Jiang, Chongming, et al.
Publicado: (2022)