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Subendothelial stiffness alters endothelial cell traction force generation while exerting a minimal effect on the transcriptome

Endothelial cells respond to changes in subendothelial stiffness by altering their migration and mechanics, but whether those responses are due to transcriptional reprogramming remains largely unknown. We measured traction force generation and also performed gene expression profiling for two endothe...

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Detalles Bibliográficos
Autores principales: Bastounis, Effie E., Yeh, Yi-Ting, Theriot, Julie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890669/
https://www.ncbi.nlm.nih.gov/pubmed/31796790
http://dx.doi.org/10.1038/s41598-019-54336-2