Targeting ARID1A-mutant colorectal cancer: depletion of ARID1B increases radiosensitivity and modulates DNA damage response

The SWI/SNF chromatin remodeling complex has been found mutated in a wide range of human cancers, causing alterations in gene expression patterns, proliferation and DNA damage response that have been linked to poor clinical prognosis. Here, we investigated weather knockdown of ARID1B, one of two mut...

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Detalles Bibliográficos
Autores principales: Niedermaier, B., Sak, A., Zernickel, E., Xu, Shan, Groneberg, M., Stuschke, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890697/
https://www.ncbi.nlm.nih.gov/pubmed/31796878
http://dx.doi.org/10.1038/s41598-019-54757-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890697/
https://www.ncbi.nlm.nih.gov/pubmed/31796878
http://dx.doi.org/10.1038/s41598-019-54757-z

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