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Indirubin-pregnane X receptor-JNK axis accelerates skin wound healing

Indirubin is a potent anti-inflammatory phytochemical derived from indigo naturalis. It is also endogenously produced in the intestine and detected in the circulation in mammals. Indirubin exerts its biological functions via two xenobiotic receptor systems: aryl hydrocarbon receptor (AHR) and pregna...

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Detalles Bibliográficos
Autores principales: Tanaka, Yuka, Uchi, Hiroshi, Ito, Takamichi, Furue, Masutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890704/
https://www.ncbi.nlm.nih.gov/pubmed/31796845
http://dx.doi.org/10.1038/s41598-019-54754-2