Prenatal Glucocorticoid Exposure Results in Changes in Gene Transcription and DNA Methylation in the Female Juvenile Guinea Pig Hippocampus Across Three Generations

Synthetic glucocorticoids (sGC) are administered to women at risk for pre-term delivery, to mature the fetal lung and decrease neonatal morbidity. sGC also profoundly affect the fetal brain. The hippocampus expresses high levels of glucocorticoid (GR) and mineralocorticoid receptor (MR), and its dev...

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Detalles Bibliográficos
Autores principales: Constantinof, Andrea, Boureau, Lisa, Moisiadis, Vasilis G., Kostaki, Alisa, Szyf, Moshe, Matthews, Stephen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890750/
https://www.ncbi.nlm.nih.gov/pubmed/31796763
http://dx.doi.org/10.1038/s41598-019-54456-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890750/
https://www.ncbi.nlm.nih.gov/pubmed/31796763
http://dx.doi.org/10.1038/s41598-019-54456-9

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