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Screening of X-ray responsive substances for the next generation of radiosensitizers

X-ray responsivity resulting in the generation of reactive oxygen species (ROS) was investigated in 9600 organic compounds that were selected by considering their structural diversity. We focused on superoxides that were primarily detected using dihydroethidium (DHE) and hydroxyl radicals, that were...

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Detalles Bibliográficos
Autores principales: Moriyama, Akihiro, Hasegawa, Takema, Jiang, Lei, Iwahashi, Hitoshi, Mori, Takashi, Takahashi, Junko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890787/
https://www.ncbi.nlm.nih.gov/pubmed/31796788
http://dx.doi.org/10.1038/s41598-019-54649-2