Pulmonary PET imaging confirms preferential lung target occupancy of an inhaled bronchodilator

BACKGROUND: Positron emission tomography (PET) is a non-invasive molecular imaging technique that traces the distribution of radiolabeled molecules in experimental animals and human subjects. We hypothesized that PET could be used to visualize the binding of the bronchodilator drug ipratropium to mu...

Descripción completa

Detalles Bibliográficos
Autores principales: Schou, Magnus, Ewing, Pär, Cselenyi, Zsolt, Fridén, Markus, Takano, Akihiro, Halldin, Christer, Farde, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890867/
https://www.ncbi.nlm.nih.gov/pubmed/30694407
http://dx.doi.org/10.1186/s13550-019-0479-8