Drug Repurposing of Bromodomain Inhibitors as Potential Novel Therapeutic Leads for Lymphatic Filariasis Guided by Multispecies Transcriptomics

To better understand the transcriptomic interplay of organisms associated with lymphatic filariasis, we conducted multispecies transcriptome sequencing (RNA-Seq) on the filarial nematode Brugia malayi, its Wolbachia endosymbiont wBm, and its laboratory vector Aedes aegypti across the entire B. malay...

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Detalles Bibliográficos
Autores principales: Chung, Matthew, Teigen, Laura E., Libro, Silvia, Bromley, Robin E., Olley, Dustin, Kumar, Nikhil, Sadzewicz, Lisa, Tallon, Luke J., Mahurkar, Anup, Foster, Jeremy M., Michalski, Michelle L., Dunning Hotopp, Julie C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890932/
https://www.ncbi.nlm.nih.gov/pubmed/31796568
http://dx.doi.org/10.1128/mSystems.00596-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890932/
https://www.ncbi.nlm.nih.gov/pubmed/31796568
http://dx.doi.org/10.1128/mSystems.00596-19

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